Mercedes-Benz S-class Sedan
09.2005 - 05.2009 · Europe
Generation 5, W221
V221, W221
Compare the engine, transmission and drive layout. Open a version name for detailed specifications and equipment.
View specifications ↓Choosing a Mercedes-Benz S-class
Mercedes-Benz S-class, Generation 5, W221, Europe market. This overview covers 26 recorded trim entries associated with this generation (09.2005 - 05.2009). The same trim name may occur in several production periods.
Compare the engine, transmission and drive layout within a single trim. Ranges below combine the populated records of different versions; they do not replace the specifications of the selected car.
Overview based on recorded specifications: 26 trim entries. Specification source ↗
- Seats
- 5
- Engine codes
- M 156 E 63, M 272 E 35, M 273 E 46, M 273 E 55, M 275 E 55 LA, M 275 E 60 AL, OM 629 DE 40 LA, OM 642 DE 30 LA
- Engine displacement, cc
- 2987–6208
- Drive layout
- Rear-wheel drive, All-wheel drive (4WD)
- Transmission
- Automatic 5, Automatic 7, Automated manual 5, Automated manual 7
- Wheelbase, mm
- 3035–3165
- Ground clearance, mm
- 146
- Fuel
- Petrol Premium (AI-98), Petrol AI-95, Petrol AI-98, Diesel
Equipment and practical details
Mercedes-Benz S-class · Generation 5, W221 · Europe · 09.2005 - 05.2009. These features occur in different versions of this generation. They are not a shared specification for every car: check the selected trim for the equipment you need and how it operates.
- Air suspension
- Check the vehicle after it has been parked and test available adjustments. Confirm which axle has air springs.
- Blind-spot monitoring
- Check the mirror indicators and system settings. Operating conditions depend on the specification and are described in the vehicle manual.
Specifications and technical details
26 versions3.0 L, 235 hp, diesel, automatic transmission, rear-wheel drive
OM 642 DE 30 LA · АКПП 7 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 320 CDI AT LTop grade | 09.2005 - 11.2008 | |
| S 320 CDI ATBase grade | 09.2005 - 11.2008 | |
| S 320 CDI BlueEFFICIENCY ATBase grade | 12.2008 - 05.2009 | |
| S 320 CDI BlueEFFICIENCY AT LTop grade | 12.2008 - 05.2009 |
3.0 L, 235 hp, diesel, automatic transmission, all-wheel drive (4WD)
OM 642 DE 30 LA · АКПП 7 · All-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 320 CDI AT 4MATICBase grade | 09.2005 - 11.2008 | |
| S 320 CDI AT L 4MATICTop grade | 09.2005 - 11.2008 | |
| S 320 CDI BlueEFFICIENCY AT 4MATICBase grade | 12.2008 - 05.2009 | |
| S 320 CDI BlueEFFICIENCY AT L 4MATICTop grade | 12.2008 - 05.2009 |
4.0 L, 320 hp, diesel, automatic transmission, rear-wheel drive
OM 629 DE 40 LA · АКПП 7 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 420 CDI ATBase grade | 09.2005 - 05.2009 | |
| S 420 CDI AT LTop grade | 09.2005 - 05.2009 |
3.5 L, 272 hp, petrol, automatic transmission, rear-wheel drive
M 272 E 35 · АКПП 7 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 350 ATBase grade | 09.2005 - 05.2009 | |
| S 350 AT LTop grade | 09.2005 - 05.2009 |
3.5 L, 272 hp, petrol, automatic transmission, all-wheel drive (4WD)
M 272 E 35 · АКПП 7 · All-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 350 AT 4MATICBase grade | 09.2005 - 05.2009 | |
| S 350 AT L 4MATICTop grade | 09.2005 - 05.2009 |
4.7 L, 340 hp, petrol, automatic transmission, rear-wheel drive
M 273 E 46 · АКПП 7 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 450 ATBase grade | 10.2006 - 05.2009 | |
| S 450 AT LTop grade | 10.2006 - 05.2009 |
4.7 L, 340 hp, petrol, automatic transmission, all-wheel drive (4WD)
M 273 E 46 · АКПП 7 · All-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 450 AT 4MATICBase grade | 10.2006 - 05.2009 | |
| S 450 AT L 4MATICTop grade | 10.2006 - 05.2009 |
5.5 L, 388 hp, petrol, automatic transmission, rear-wheel drive
M 273 E 55 · АКПП 7 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 500 ATBase grade | 09.2005 - 05.2009 | |
| S 500 AT LTop grade | 09.2005 - 05.2009 |
5.5 L, 388 hp, petrol, automatic transmission, all-wheel drive (4WD)
M 273 E 55 · АКПП 7 · All-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 500 AT 4MATICBase grade | 09.2005 - 05.2009 | |
| S 500 AT L 4MATICTop grade | 09.2005 - 05.2009 |
5.5 L, 517 hp, petrol, automatic transmission, rear-wheel drive
M 275 E 55 LA · 5-speed automatic · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 600 AT L | 09.2005 - 05.2009 |
6.2 L, 525 hp, petrol, automated transmission, rear-wheel drive
M 156 E 63 · 7-speed automated manual · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 63 DSG AMG | 06.2006 - 05.2009 | |
| S 63 DSG AMG L | 11.2006 - 05.2009 |
6.0 L, 612 hp, petrol, automated transmission, rear-wheel drive
M 275 E 60 AL · РКПП 5 · Rear-wheel drive
| Specification | Production period | Compare |
|---|---|---|
| S 65 DSG AMG L | 11.2006 - 05.2009 |
Choose 2–3 versions to compare
Go to comparison ↓Mercedes-Benz S-class comparison
Compare up to three versions of one model.
Select Add to comparison for the required versions above. Versions from different generations can be compared.
The catalog helps compare vehicles. It does not show availability or the price of a specific lot. Vehicle age is based on the production date; the final estimate is prepared for the selected vehicle.